Multi-Echo Sequences and Resting-State fMRI

Discussion of Lynch et al. (2020) regarding the use of multi-echo sequences to improve reliability in resting-state fMRI: https://www.cell.com/cell-reports/pdf... Talk given at the NII-Methods symposium, November 1st, 2024 Table of Contents ============== 0:00 Introduction and History of Resting-State Connectivity 3:09 Clinical Applications of Resting-State Analysis 5:47 Issues with Resting-State Data and Reliability 12:27 Overview of the Lynch et al. (2020) Study and Multi-Echo Sequences 15:53 Review of Reliability of Single-Echo Comparison Studies 18:13 Advantages of Combining Multi-Echo and AROMA Independent Components Analysis for Denoising 24:40 Reliability Curves of Multi-Echo vs. Single-Echo Sequences 29:02 Reliability of Networks for Multi-Echo vs. Single-Echo 32:10 Limitations and Summary 37:50 General Discussion about Using Multi-Echo and Multiband Sequences at the University of Michigan