NOD2 Effect on Crohn’s Disease

In this video I describe what NOD 2 does and how mutations affect the body and causes Crohn’s dz. #crohnsdisease #dreldersanatomychannel #gastroenterology #medicalpathology Research I used NOD2 mutation can lead to alternative pathway https://pmc.ncbi.nlm.nih.gov/articles.... Cytokines released in the alternate pathway https://www.frontiersin.org/journals/... Toll like receptors activate NLRP3 inflammosome in crohns https://pubmed.ncbi.nlm.nih.gov/2509/ Toll like receptors are on cell membranes of macrophages and epithelial cells https://pmc.ncbi.nlm.nih.gov/articles.... Role of NOD2 and ATG16L1 https://www.dovepress.com/nod2-and-in...