The Elizabeth Holmes Theranos Deposition | Part 2

In Part 2 of Elizabeth Holmes’ official SEC deposition regarding Theranos, federal investigators press the founder and former CEO on the inner workings of the company’s blood-testing technology. Under questioning, Holmes addresses the reality behind the "miniLab" (TSPU), the company’s reliance on modified third-party commercial analyzers (including Siemens Advia machines), and how few tests were actually validated or running in the clinical lab during the Walgreens rollout. Investigators also examine internal emails with Sunny Balwani, investor demonstrations, and the strategic shift between Theranos's public promises and laboratory realities. Subscribe to Hidden Killers With Tony Brueski for deep dives, trial coverage, and primary-source depositions from the biggest true-crime and corporate fraud cases. Timestamps 00:00 – "Lab in a Box": The TSPU & MiniLab Concept 00:44 – Commercial Testing Launch & Open Platforms (2013) 03:48 – Modifying Third-Party Analyzers (Siemens Advia 1800) 06:00 – The Three Categories of Lab Machines 08:40 – High-Throughput Centralized Labs vs. Point-of-Care 11:00 – Discrepancy: 15 Clinical Tests vs. 90 "Validated" Assays 15:26 – FDA Guidelines vs. CLIA Validation Standards 18:35 – Running Tests on Modified Commercial Machines 22:53 – Exhibit 197: Internal Emails, Demos, and the "Normandy Shell" 31:45 – "Null Protocols" and Technology Demonstrations 37:05 – Cartridge Barcodes & Running Dummy Test Programs 38:20 – Issues with MiniLab 4S Performance 43:40 – Exhibit 198: January 2014 FDA Communications & The 4 Active Assays 48:00 – Exhibit 199: PFM Lawsuit Interrogatories & The 12 TSPU Tests 54:36 – Phase 1 vs. Phase 2 Business Model Explained 58:00 – Exhibit 200: Supplemental Discovery & Hardware Iterations 01:05:43 – Exhibit 201: The 4 Modified Commercial Machines & CBC Panels 01:15:35 – Disclosures to Investors, Walgreens, and Safeway Regarding Third-Party Machines 01:18:50 – Why the Nanotainer Was Really Created 01:25:05 – Venipuncture vs. Fingerstick Disclosures 01:35:10 – Staging Technology Demos for Investors & Partners 01:41:00 – Demonstrations vs. Clinical Lab Samples at 1601 01:57:45 – The Safeway Multi-Bay Concept 02:00:30 – Dropping Tests to Avoid Venous Blood Draws during Demos Listen To Hidden Killers Podcast ANYWHERE! Listen Here: https://linktr.ee/hiddenkillers Join Our SubStack For AD-FREE ADVANCE EPISODES & EXTRAS!: https://hiddenkillers.substack.com/ Instagram   / hiddenkillerspod   Facebook   / hiddenkillerspod   Tik-Tok   / hiddenkillerspod   X Twitter https://x.com/tonybpod This publication contains commentary and opinion based on publicly available information. All individuals are presumed innocent until proven guilty in a court of law. Nothing published here should be taken as a statement of fact, health or legal advice.