Rheumatoid Arthritis (RA) | Definition, Pathogenesis, Diagnosis & Treatment

Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease that primarily affects synovial joints. This video covers the essential clinical framework of RA, including pathophysiology, clinical features, ACR/EULAR classification, investigations, disease activity, differential diagnosis, and treatment. Designed for medical students, healthcare professionals, and anyone interested in understanding rheumatoid arthritis clearly and systematically. Educational content only. ABOUT MJ KIM • 5th-year Medical Student • BBA, BSc, MSc 📚 References • Aletaha D, Neogi T, Silman AJ, et al. 2010 Rheumatoid Arthritis Classification Criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative. Annals of the Rheumatic Diseases. 2010;69:1580–1588. • Smolen JS, Landewé RBM, Bergstra SA, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological DMARDs: 2022 update. Annals of the Rheumatic Diseases. 2023;82:3–18. Arthritis Research & Therapy • National Institute for Health and Care Excellence (NICE). Rheumatoid arthritis in adults: management. NICE Guideline NG100. Nice • Fraenkel L, Bathon JM, England BR, et al. 2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis. Arthritis Care & Research. 2021;73:924–939. • NHS. Rheumatoid arthritis: diagnosis and treatment. NHS guidance notes that no single blood test definitively confirms or excludes RA and describes the role of ESR, CRP, RF, anti-CCP and imaging. #RheumatoidArthritis #Rheumatology #AutoimmuneDisease #MedicalEducation #MedicalStudent #Arthritis #Pathophysiology #ClinicalMedicine #DMARDs #Medicine