When Benign Turns Malignant

Dr. Sepideh Abdi reviews the key imaging features of premalignant bone and soft-tissue conditions, highlighting how radiologists can recognize early signs of malignant transformation in benign tumors and chronically injured tissues. From osteochondromas and enchondromas to neurofibromas, atypical lipomatous tumors, and radiation-induced sarcomas, this episode provides practical takeaways for identifying imaging findings that warrant closer evaluation and intervention. Imaging of Premalignant Conditions ofBone and Soft Tissue. Abdi et al. RadioGraphics 2025; 45(8):e240172. (https://doi.org/10.1148/rg.240172)