Neurology Classroom Ep 2 | Imaging & Clinical Decision-Making in Acute Stroke | Dr. Khwaja Siddiqui

What does it take to make the right clinical decision when every minute matters in acute stroke? In Episode 2 of the Neurology Classroom, Sakina Shaikh sits down with Dr. Khwaja A. Siddiqui, Assistant Professor at Baylor College of Medicine, to explore the practical approach to imaging and clinical decision-making in acute stroke. From identifying the last known well time to interpreting non-contrast CT, CTA, CT perfusion, and MRI, this episode takes trainees beyond simply “looking at the scan” and focuses on how imaging findings translate into urgent treatment decisions. In this episode, we discuss: The initial clinical evaluation of a patient with suspected acute stroke Why “time is brain” and why last known well time matters Distinguishing acute stroke from stroke mimics such as seizures How to approach non-contrast CT in the emergency stroke setting Understanding ASPECTS and early ischemic changes Recognizing hyperdense vessel signs When and why to obtain CTA and CT perfusion The role of MRI and MRA in acute stroke evaluation Imaging considerations for thrombolysis with alteplase or tenecteplase Selecting patients for mechanical thrombectomy Understanding the early- and late-window approaches to thrombectomy The role of AI in cerebrovascular imaging and personalized stroke care Practical advice for trainees and international medical graduates pursuing neurology Dr. Siddiqui also shares insights into the evolving field of vascular neurology, the growing role of artificial intelligence in stroke care, and the importance of curiosity, persistence, and perseverance for trainees pursuing a career in neurology. Neurology Classroom Podcast brings clinicians, educators, and experts together to explore the science, practice, and human side of neurology. 📚 Educational content for medical students, residents, fellows, and anyone interested in neurology. #NeurologyClassroom #AcuteStroke #Stroke #VascularNeurology #Neurology #StrokeImaging #MedicalEducation #NeurologyPodcast