Von Willebrand Disease Quick Review | VWF Antigen, Activity & Factor VIII

Description: How is von Willebrand disease (VWD) diagnosed in the laboratory? In this video, we break down the diagnostic approach to VWD, including VWF antigen (VWF:Ag), VWF activity, Factor VIII levels, activity-to-antigen ratio, and further testing used to differentiate the different types of VWD. A practical and exam-focused review for hematology residents, pathology trainees, laboratory professionals, and medical students. Topics covered: • Initial laboratory evaluation of suspected VWD • VWF antigen vs VWF activity • Factor VIII assessment • Activity-to-antigen ratio • Differentiating quantitative and qualitative VWF defects • Approach to VWD subtyping #VonWillebrandDisease #VWD #Hematology #Coagulation #BleedingDisorders #VWF #FactorVIII #LaboratoryMedicine #HematologyEducation