NAPLEX Practice Questions 2026-2027: 100-Question Mock Exam with Answers

NAPLEX practice questions at real exam difficulty: a full 100-question NAPLEX mock exam with the answer and a detailed explanation after every question. Pause, answer, then check yourself. This is MedPrepPrime NAPLEX Mock Exam 1. It follows the current NABP NAPLEX Content Outline (in effect since May 2025) and matches its domain weights, so you practice the same mix you will see on test day: Foundational Knowledge for Pharmacy Practice: 25 questions Medication Use Process: 25 questions Person-Centered Assessment and Treatment Planning: 40 questions Professional Practice: 5 questions Pharmacy Management and Leadership: 5 questions WHAT YOU GET ✔ 100 exam-level questions: patient cases, direct-recall items, 12 pharmacy calculations and ordered-response (ranking) items ✔ The correct answer, plus why each wrong option is wrong ✔ Every calculation worked step by step ✔ Content checked against FDA labeling and clinical guidelines current as of October 2026 TIMESTAMPS / STUDY CHAPTERS: 0:00 - Intro & Mock Exam Rules 0:24 - Questions 1–10: Cardiology & Pharmacotherapy Calculations 16:45 - Questions 11–20: Infectious Diseases & Antimicrobials 33:30 - Questions 21–30: Endocrine & Renal Management 50:15 - Questions 31–40: Psychiatry & Neurology 1:07:00 - Questions 41–50: Oncology & Supportive Care 1:23:45 - Questions 51–60: USP Compounding & Formulations (795/797/800) 1:40:30 - Questions 61–70: Pharmacy Math & Biostatistics 1:57:15 - Questions 71–80: Pulmonary & Critical Care 2:14:00 - Questions 81–90: Toxicology, Overdose & Antidotes 2:30:45 - Questions 91–100: Immunizations & General Practice Review Detailed Question-by-Question Breakdown of timestamps is in the pinned comments. Want more questions like these? NAPLEX practice tests and question banks: https://medprepprime.com/naplex-pract... Think an answer deserves a second look? Post the question number and your reasoning. We read every comment and reply. Mock Exam 2 is coming. Subscribe so you don't miss it. TOPICS COVERED Cardiology, anticoagulation, diabetes, infectious diseases and antimicrobial stewardship, HIV, oncology supportive care, psychiatry, neurology, transplant, toxicology, immunizations, women's health, pediatrics, pain management, OTC and self-care, pharmacokinetics, pharmacogenomics, biostatistics, sterile and nonsterile compounding (USP 795, 797 and 800), medication safety, drug information and pharmacy calculations. HOW TO USE THIS VIDEO 1. Pause when each question appears and commit to an answer. The real NAPLEX gives you about 96 seconds per question. 2. Play on for the answer and explanation. 3. Keep a tally, then use the chapters below to revisit your weak areas. 4. Comment your score out of 100. MORE NAPLEX PREP ▶ NAPLEX practice tests and question banks: https://medprepprime.com/naplex-pract... ▶ More NAPLEX videos: https://medprepprime.com/naplex-videos/ ▶ Subscribe so you don't miss Mock Exam 2:    / @medprepprime   ABOUT THE NAPLEX The North American Pharmacist Licensure Examination is a 6-hour, 225-question computer-based exam; 200 questions are scored. This video is a 100-question practice set built to the same blueprint for PharmD graduates, pharmacy students on rotations and foreign pharmacy graduates. Want to discuss a question? Comment the question number and we will reply. DISCLAIMER For exam preparation only; not medical advice. NAPLEX and NABP are registered trademarks of the National Association of Boards of Pharmacy, which is not affiliated with and does not endorse this video. All questions are original and are not actual exam items. #NAPLEX #NAPLEXPrep #PharmD