INICET Predictor Series | Gen-Pathology by Dr. Shagun Mehta
DAMS : NEET PG, MBBS, FMGE, USMLE Prep
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INICET Predictor Series | Gen-Pathology by Dr. Shagun Mehta
12 292 просмотра · Трансляция закончилась 1 год назад
DAMS : NEET PG, MBBS, FMGE, USMLE Prep
961 тыс. подписчиков
12 292 просмотра · Трансляция закончилась 1 год назад
General Pathology & Important Concepts for Exams
Timestamps & Key Topics Covered:
Introduction & Overview
0:28 - Greetings & Introduction
0:34 - Checking audio/video clarity before proceeding
2:27 - Discussion on predicted questions for General Pathology (Hematology completed)
Important Stains in Pathology
4:02 - Match the following: Stains for Melanin, Copper, Collagen, Calcium
4:21 - Melanin: Masson-Fontana stain
4:42 - Copper: Rhodanine stain
5:08 - Collagen: Mason-Trichrome stain
5:14 - Calcium: Von Kossa stain
5:45 - Other important stains:
Hemosiderin: Prussian Blue
Glycogen: PAS (Periodic Acid-Schiff)
Amyloid: Congo Red (Apple-green birefringence under polarized light)
Amyloidosis & Types
7:41 - Amyloid types and associated diseases:
AL (Light chain) – Multiple Myeloma
Aβ2M (Beta-2 Microglobulin) – Hemodialysis-associated
ATTR (Transthyretin) – Familial Amyloidotic Polyneuropathy
Aβ (Amyloid Beta) – Alzheimer’s disease
Genetic Disorders
10:14 - Angelman Syndrome:
"Happy Puppet" syndrome (inappropriate laughter, ataxic movements)
Genomic imprinting disorder (maternal deletion)
15:24 - Prader-Willi Syndrome: Paternal deletion
19:06 - Inheritance Patterns:
Autosomal Dominant (e.g., Familial Adenomatous Polyposis)
Mitochondrial Inheritance (Maternal transmission only)
Paraneoplastic Syndromes
16:22 - Match the following:
SIADH – Small Cell Lung Carcinoma
Acanthosis Nigricans – Gastric Carcinoma
Myasthenia Gravis – Thymoma
Hypercalcemia – Squamous Cell Lung Carcinoma
Necrosis vs. Apoptosis
34:00 - Coagulative Necrosis (Heart, Kidney, Liver)
35:26 - Apoptosis Features:
Cell shrinkage (no inflammation)
Caspase activation
Annexin V marker
Oncogenes & Tumor Suppressors
1:03:48 - Important Oncogenes:
RET – Medullary Thyroid Carcinoma
HER2/neu – Breast Cancer
RAS – Colon/Pancreatic Cancer
1:06:01 - Tumor Suppressors:
TP53 (Li-Fraumeni Syndrome)
RB (Retinoblastoma)
APC (Colorectal Cancer)
Carcinogens & Associated Cancers
56:39 - Chemical Carcinogens:
Asbestos – Mesothelioma
Aflatoxin – Hepatocellular Carcinoma
DES (Diethylstilbestrol) – Clear Cell Carcinoma (Vagina)
Cell Injury & Adaptations
1:20:43 - Reversible Injury:
Mitochondrial dysfunction (earliest change)
Membrane blebs
1:22:04 - Irreversible Injury:
Nuclear changes (Pyknosis → Karyorrhexis → Karyolysis)
Final Tips & Motivation
1:26:10 - Last-minute revision advice
1:27:48 - Overcoming exam stress & staying focused
Key Takeaways:
High-yield tables for stains, amyloid types, and genetic disorders.
Must-know oncogenes, tumor suppressors, and carcinogens.
Clear differentiation between necrosis and apoptosis.
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