Isaac Unlocks #12 - Daily run with Cain to Beast, Diplopia GOD play with Sulfur

Broadcasted live on Twitch -- Watch live at   / spideybr   The Binding of Isaac: Repentance+, going for all achievements! The daily run for September 17th, 2026. Cain has to go all the way to The Beast! I made an AMAZING play with Diplopia that unlocked the whole run. Check it out!