Semiconservative DNA Replication: Meselson-Stahl Experiment Explained!

What happens to the original DNA during DNA replication? What does the Meselson-Stahl experiment tell us? And what do all of those little tubes mean? Let's see! The Meselson-Stahl experiment shows us that DNA replication is semi-conservative - that when a molecule of DNA is copied, each strand is used as a template to create a new strand, resulting in two double-stranded daughter molecules. In this video, we'll walk through the importance of DNA density in this experiment, making predictions about what we'd expect to see in the tubes for different models of DNA replication, and comparing with what Meselson and Stahl actually observed. #MeselsonStahl #DNAreplication #SemiConservative #MeselsonAndStahl In this video: 00:00 Intro 00:22 Semi-conservative DNA replication model 00:45 Conservative DNA replication model 00:55 Dispersive DNA replication model 01:21 Meselson-Stahl experimental question 01:44 Use of nitrogen isotopes in Meselson-Stahl 02:32 Density gradients and DNA 04:00 "Light" DNA and "Heavy" DNA 04:27 DNA replication is not conservative: Meselson-Stahl Generation 1 tubes 06:04 DNA replication is not dispersive: Meselson-Stahl Generation 2 tubes 07:40 Meselson-Stahl extra generations 08:10 Review: Pattern observed by Meselson and Stahl Related Videos: Chargaff's Rules: Review and Practice:    • Chargaff's Rules: Review and Practice   7 Must-Know Parts of DNA Structure:    • The DNA Double Helix: What's In There?   DNA or Protein? How Hershey and Chase Changed Biology:    • DNA or Protein? How Hershey and Chase Chan...   New videos are always on the way - subscribe so you don't miss any of my biology tips :) Connect with me! Website: http://www.yourotherbioprof.com Instagram: instagram.com/yourotherbioprof