What we know about ANA negative Lupus and how to navigate this tricky situation

ANA-negative lupus exists, but it’s complicated. Many people struggle with confusing test results and conflicting information. Learn why ANA testing isn’t always straightforward, how other antibodies like anti-dsDNA and anti-Smith can help, and how focusing on symptoms and lifestyle changes can improve your quality of life. 💻 https://connectedrheumatology.com/ Visit the Connected Rheumatology website and get your Appointment Home Run Handbook, the guide you need to tell your doc your story -and get answers once and for all! 🎥 watch more: 5 facts about your +dsDNA antibody -    • 5 Facts about your +dsDNA antibody   The anti-Smith antibody in lupus -    • The anti-Smith antibody in Lupus   Learn about common lupus symptoms -    • Learn about Common Lupus Symptoms   💡Video Key Takeaways ✔️ ANA negative lupus exists but is complex.. ✔️ ANA testing variability contributes to confusion, making understanding the type of ANA test performed important when deciphering its results. ✔️ Other antibodies, such as the anti-dsDNA and anti-Smith (known as ENA antibodies) can provide clues, even if the ANA is negative. ✔️When test results conflict, prioritizing symptoms, their timeline, and a detailed personal and family medical history can guide doctors in assessing the likelihood of lupus. ✔️ Even without a definitive diagnosis, trying treatments like prednisone or hydroxychloroquine, or focusing on lifestyle changes (e.g., improved sleep, stress management, and an anti-inflammatory diet), can improve symptoms and quality of life. ⏱️Time Stamps: 0:00 Intro 1:06 The problem with testing 4:12 Other antibody results 6:09 Making sense of it all 9:39 Making a plan without all the answers 📖 References: Pisetsky DS, Lipsky PE. New insights into the role of antinuclear antibodies in systemic lupus erythematosus. Nat Rev Rheumatol. 2020 Oct;16(10):565-579. doi: 10.1038/s41584-020-0480-7. Epub 2020 Sep 3. PMID: 32884126; PMCID: PMC8456518. **Please note - we do not provide medical advice, opinions or diagnosis via email, phone or social media messaging. 👩🏻‍⚕️ About me: Hello! I am Dr. Elizabeth Ortiz and I’m so happy you are here. I am a double board certified Rheumatologist with over 18 years experience practicing Rheumatology and am passionate about teaching & empowering patients to partner with their doctor. * The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a consultation with your own doctor/health professional. Any comments and/or recommendations made in the comment section by anyone other than Connected Rheumatology does not reflect the opinion or recommendation of Connected Rheumatology.*