Physical Carcinogenesis Explained | UV & Ionizing Radiation

Physical carcinogenesis refers to cancer development caused by physical agents, particularly radiation. In this video, we discuss the important mechanisms by which physical agents can cause DNA damage, mutations, genomic instability and ultimately malignancy. 00:00 Introduction 00:30 Carcinogenesis explained 04:30 Carcinogens 12:55 Ames test 18:15 UV light 22:05 Ionizing radiation 29:40 Non-neoplastic conditions We will cover: Ultraviolet (UV) radiation — DNA damage, pyrimidine dimers and skin cancers Ionizing radiation — direct and indirect DNA damage Role of DNA repair defects and genomic instability Mechanisms linking radiation exposure to carcinogenesis Examples of cancers associated with radiation exposure Important non-neoplastic effects of radiation This video is useful for MBBS, NEET-PG, INI-CET, pathology and medical students preparing the topic of carcinogenesis/neoplasia. #PhysicalCarcinogenesis #Carcinogenesis #Pathology #Cancer #Radiation #UVRadiation #IonizingRadiation #DNA damage #DNARepair #CancerBiology #Neoplasia #MedicalEducation #MBBS #NEETPG #INICET