S7 Ep 11: It Starts With the Egg: The Science of Egg Quality, Mitochondria & Fertility with Dr. A...

What determines the health of our eggs, and can we do anything to support them? In this fascinating episode of The Hormone Genius Podcast, Teresa and Jamie welcome Dr. Alison Ermisch, PhD, Education Programs Manager at FACTS About Fertility, to explore the incredible science of ovarian physiology, egg quality, and the earliest moments of human development. Dr. Ermisch holds a PhD in reproductive physiology from the University of Nebraska–Lincoln, with research focused on oocyte metabolism and ovarian physiology. She explains how egg development begins before birth, why the final months of an egg’s maturation matter, and how our metabolic health can influence the environment in which eggs grow. We dive into the role of mitochondria, the energy-producing powerhouses of the egg, and how oxidative stress and inflammation may disrupt the delicate cellular processes necessary for healthy development. You'll also learn what happens when sperm meets egg, how fertilization initiates early embryonic development, and the fascinating science behind the “zinc spark” associated with fertilization. So, what can women do to support their reproductive health? Dr. Ermisch emphasizes the importance of understanding your menstrual cycle, getting adequate sleep, eating well, and recognizing how metabolic and hormonal health are interconnected. Teresa and Jamie also discuss lifestyle factors, environmental exposures, and nutrients often explored in conversations about egg health. Dr. Ermisch shares her own experience with miscarriage and progesterone support, highlighting why identifying and treating underlying reproductive health concerns matters. Her work with FACTS About Fertility is helping educate future physicians about fertility awareness, cycle charting, and the menstrual cycle as a vital sign. Whether you're preparing for pregnancy, navigating infertility, or simply want to understand your body more deeply, this episode offers a remarkable look at the biology of fertility and the importance of whole-body health. FACTS About Fertility: Upcoming Virtual Conference Join FACTS About Fertility November 20–21, 2026, for its virtual conference featuring research and clinical insights into fertility awareness and reproductive health. Dr. Ermisch is among the featured speakers! Healthcare professionals, medical students, and fertility educators are encouraged to attend. CME options are available. Register: https://www.factsaboutfertility.org/2... Our Sponsors We Heart Nutrition — Thoughtfully formulated supplements to support your wellness journey. Visit https://www.weheartnutrition.com and use code GENIUS at checkout for 20% off! Radiant Clinic — Looking for personalized support for menstrual concerns, hormone health, infertility, or recurrent pregnancy loss? Radiant Clinic uses a restorative reproductive medicine approach to investigate underlying causes and support women's health. Free discovery calls are available. Learn more: https://radiantclinic.com Medical Disclaimer: This podcast is for educational purposes only and is not a substitute for individualized medical advice, diagnosis, or treatment. Consult your healthcare professional before making changes to your care or starting supplements.