Rooms Without Walls: Cancer's Hidden Architecture

This episode recaps a conversation with Forbeck Forum co-chairs Dr. Liling Wan (UPenn) and Dr. Benjamin Sabari (UT Southwestern) about the science behind their upcoming forum on nuclear condensates in cancer. Condensates are membrane-free compartments cells use to concentrate proteins and RNA — and they play a major role in switching genes on and off. When that process goes wrong, oncogenes activate and tumor suppressors go silent. The recap covers how this forum moves the field from foundational biophysics toward translational questions: what condensates actually do in disease, and how researchers might target the ones driving cancer.