RayHub at ESTRO 2026: Reirradiation- From Challenges to Solutions

Subject to regulatory clearance in some markets. Functionality available can differ depending on scope of regulatory clearance, refer to your local vendor for available functionality in your country. 🎤Presenters: Ane Appelt, Professor of Clinical Medical Physics, Rigshospitalet &; Technical University of Denmark Rasmus Bokrantz, Head of Algorithm Development, RaySearch Laboratories Moderator: Jakob Ödén, Research Engineer, RaySearch Laboratories This session from RayHub at ESTRO explores the complexities of reirradiation planning in radiotherapy. Ane Appelt Effelt discusses the increasing number of patients requiring repeat treatments due to longer survival rates and the challenges of managing anatomical changes and cumulative dose. She emphasizes the need for tools that can calculate and visualize 3D dose distributions using equivalent effective dose (EQD2). Rasmus Bokrantz then demonstrates how upcoming RayStation releases will support a streamlined workflow for reirradiation, including deformable image registration, dose accumulation, and optimization based on cumulative EQD2. The session concludes with a panel discussion on the clinical utility of these tools and the importance of institutional protocols to ensure consistency in managing uncertainties like tissue recovery and alpha-beta ratios.