4. How to add a compound in PK-Sim?

This video shows how to build a compound in PK-Sim, using midazolam as the example. What you will learn: How to enter physico-chemical properties such as lipophilicity, fraction unbound, and molecular weight How to add a metabolizing enzyme and link it to the expression profile from the previous video How to set up a renal clearance process How calculation methods for partition coefficients and cellular permeability are selected After this video, the midazolam compound is ready to be combined with the individual. ► Full playlist:    • Getting Started with PK-Sim | PBPK Modelin...   ► Tutorial materials and downloads: https://www.uni-saarland.de/en/chair/... ► Created by the PBPK Tutorial Team, Clinical Pharmacy, Saarland University