Inside Ambience: Deploying AI in Healthcare Systems

a16z general partner Julie Yoo talks with Nikhil Buduma, CEO and cofounder of Ambience Healthcare, to discuss how AI is transforming clinical workflows. They cover the early days of deep learning, why Ambience started by running a medical practice before building a platform company, and what it takes to achieve high clinician adoption rates at major academic medical centers. They also dig into the challenge of building products when AI capabilities change every few months, the real ROI that's finally converting CFOs, and why this might be the moment to reimagine the legacy EHR stack. 00:00 - Introduction 03:16 - Using Transformers in Production and Seeing the Exponential Coming 08:14 - Why Providers Went From Tech Laggards to Fastest AI Adopters 15:25 - The Last-Mile Problem: EHR Context, Decision Traces, and Defining Quality 20:30 - Agents, New Systems of Record, and Building a Layer on Top of the EHR 24:47 - From Copilot to Virtual Care Team: Expanding Access Without Burning Out Clinicians 35:37 - Proving Hard ROI: How CFOs Are Starting to Believe in AI 44:49 - Why There's Finally Hope for Clinicians, Patients, and Healthcare Follow Nikhil Buduma on X:   / nkbuduma   Follow Julie Yoo on X:   / julesyoo   Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends! Find a16z on X: https://x.com/a16z Find a16z on LinkedIn:   / a16z   Listen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RD... Listen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast... Follow our host: https://x.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.