Lac Operon | Inducible Operon Positive Negative Control | NEET Class 12 | Neela Bakore Tutorials

◀ PREVIOUS VIDEO (21/26): Regulation of Gene Expression    • Regulation of Gene Expression | Positive N...   ▶ CURRENT VIDEO (22/26): Lac Operon    • Lac Operon | Inducible Operon Positive Neg...   ▶ NEXT VIDEO (23/26): Tryptophan Operon    • Tryptophan Operon | Repressible Operon Att...   🔗 Full Playlist:    • Плейлист   ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ Lac Operon — the most tested operon in NEET! This video covers both negative and positive regulation of the lac operon with complete clarity. 📌 Topics Covered: • Structure of Lac Operon: Regulatory gene (i) + Promoter (P) + Operator (O) + Structural genes (lacZ, lacY, lacA) • Negative Control (Repressor-Operator): No lactose → active repressor binds operator → genes OFF Lactose present → allolactose binds repressor → operator free → genes ON • Positive Control (CAP/CRP): Low glucose → high cAMP → cAMP-CAP binds promoter → enhanced transcription High glucose → low cAMP → no CAP binding → reduced transcription • Catabolite repression • NEET MCQ on lac operon — all scenarios ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ Transcript with Timestamp 0:00 Lac operon: found in bacteria; for lactose metabolism; explained by Jacob & Monod 0:57 Normally in OFF mode (inducible operon) 1:26 OFF mode: I gene → inhibitor protein → binds operator → RNA Pol blocked → structural genes not transcribed 3:59 Three structural genes: Z (β-galactosidase), Y (permease), A (transacetylase) 7:03 ON mode: lactose enters cell → converted to allolactose 9:22 Allolactose binds inhibitor protein → inhibitor leaves operator → RNA Pol slides → transcription occurs 10:57 β-galactosidase, permease, transacetylase produced → lactose broken down to glucose + galactose 11:30 When lactose depleted → allolactose gone → inhibitor free → binds operator → operon turns OFF 14:32 True inducer = allolactose (not lactose itself) ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ Amazon Brand Store at https://www.amazon.in/neelabakoretuto.... Complete Study Notes (11th and 12th) are available at: https://amzn.to/3K4Li7k Complete Study Notes for 12th are available at: https://amzn.to/3PRhWjm Complete Study Notes for 11th are available at: https://amzn.to/4uw1hBa The study notes for this unit Genetics & Evolution are available at https://amzn.to/2Sh27jW The study notes for other units: - Diversity in Living World - https://amzn.to/3r8qkyH Structural Organisation in Plants and Animals - https://amzn.to/3r2cxmZ Cell: Structure and Functions - https://amzn.to/2GPagcm Plant Physiology - http://amzn.to/2EZR5HS Human Physiology - http://amzn.to/2DA46ea Reproduction - https://amzn.to/2wu43eS Biotechnology - http://amzn.to/2EZyqf9 Biology in Human Welfare https://amzn.to/4dPRZd7 Ecology https://amzn.to/3RwuOvF ____________________________________________ For business inquiries: abhibakore@gmail.com ___________________________________________ #LacOperon #InducibleOperon #JacobMonod #CAP #NEETBiology #MolecularBasisOfInheritance #Class12Biology #neelabakoretutorials