Ariana Gonzalez - Human cortical organoids for exploring gene by environment interactions in ASD

Developmental Diversity in a Dish: Ariana Marquez Gonzalez (from Jason Stein's group at UNC) on Friday May 1, 2026 shared her recent work on "A human cortical organoid framework for exploring gene by environment interactions in ASD". This work explores 115 iPSC lines in the IBIS consortium linking in vitro iPSC-derived organoid models to in vivo brain development and cognition, building on previous work exploring gene x environment interactions in the Stein lab (https://www.nature.com/articles/s4138....