FACTOR VIII INHIBITOR ASSAY – LAB MANUAL VIDEO 5

DIAGNOSIS OF HEMOPHILIA AND OTHER BLEEDING DISORDERS A LABORATORY MANUAL DIAGNOSIS OF HEMOPHILIA AND OTHER BLEEDING DISORDERS A LABORATORY MANUAL 5. INTERPRETING RESULTS FOR PATIENT SAMPLE 00:00:15 - Introduction to log-linear or semi-log graph paper 00:00:55 - Assigning the x-axis values—inhibitor concentration 00:01:02 - Assigning 100% residual FVIII, zero inhibitor 00:01:29 - Applying definition of 1 BU/ml inhibitor to plot 00:02:32 - Using plot to quantitate inhibitor in IQC sample 00:04:01 - Using plot to quantitate inhibitor in patient sample 00:06:31 - Considerations for acquired hemophilia 00:07:04 - Importance of consistent dilutions, for example when monitoring response to therapy 00:07:37 - Discussion of results of patient test sample—severe hemophilia 00:08:09 - Taking concentration of FVIII in patient sample into consideration 00:09:39 - Heat denaturing FVIII in patient samples prior to inhibitor assay 00:10:59 - Conclusion, refer back to Lab Manual