Infective Endocarditis - Treatment, Surgery and Prophylaxis - Case Study - Native Valve MSSA

This case-study video follows a senior medicine resident presenting infective endocarditis treatment, surgical timing, and prophylaxis to an attending on teaching rounds. Working through methicillin-sensitive Staphylococcus aureus native mitral valve endocarditis, and a second patient facing a prophylaxis decision, the resident reasons through antibiotic selection, the indications for valve surgery, and the two-part rule for endocarditis prophylaxis. This case study is treatment-focused; a companion video in this series covers diagnosis. Made for internal medicine residents and advanced practice providers. Chapters: 0:00 The Handoff: Five Facts That Choose Therapy 2:29 Why the Vegetation Resists Antibiotics 4:00 Empiric Therapy and the Organism-Directed Table 6:00 The Staphylococcus Row: MSSA versus MRSA 7:49 Duration, IV-to-Oral Switch and Anticoagulation 9:45 Surgical Indications and the Turn to Surgery 12:26 Ingrid and the Prophylaxis Rule 14:15 Regimens and Closing Pearls What you'll be able to do: • Identify the five facts that actually change an endocarditis treatment plan • Explain why a vegetation demands bactericidal, high-dose, prolonged therapy • Reason through organism-directed antibiotic selection at the bedside • Recognize when a medical case has become a surgical one • Apply the two-part rule that determines who needs endocarditis prophylaxis Part of Teaching Service — Hospital Rounds: education for residents and advanced practice providers. For clinician and trainee education only. Not medical advice; verify against current guidelines and institutional protocols before applying to patient care. #InfectiveEndocarditis #MSSA #CardiacSurgery #CaseStudy #Endocarditis #Prophylaxis #InternalMedicine #ClinicalReasoning #MedEd #ResidencyTraining