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DISCOVER the influence of expression levels on binding kinetics with scIC

Bruker Dynamic Biosensors

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DISCOVER the influence of expression levels on binding kinetics with scIC

40 просмотров · 4 месяца назад
Bruker Dynamic Biosensors
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40 просмотров · 4 месяца назад
This is the first episode of our third season of the DISCOVER MOLECULAR INTERACTIONS webinar series. Each month we will talk about cutting-edge drug discovery topics like bispecific antibodies, PROTACs or small molecules targeting RNA. We will show you how to characterize the respective molecular interactions in depth, how to create assays with remarkable biological similarity, low sample consumption, high versatility and exceptional ease-of-use. In this episode we are joined by Dr. Nichole Cerutti, Director of Biophysics at RoukenBio. Nichole will showcase the innovative IndEx-2 system which allows the control of protein expression levels on cells. Single-cell Interaction Cytometry (scIC) was used to characterize the binding of targeted therapeutics, demonstrating the effects of different target expression levels on binding kinetics. If you are interested in another application, you can find all future episodes of this webinar series here: https://www.dynamic-biosensors.com/we... Research Use Only. Not for use in clinical diagnostic procedures.