NFL Week 5 Preview: 49ers-Seahawks, Ravens-Falcons, Bills-Rams & More

NFL Week 5 is here, and Ray & J are breaking down the biggest games, storylines and fantasy football implications across the weekend. Can the undefeated 49ers survive a massive NFC West showdown with Seattle? Will Lamar Jackson be available against a suddenly dangerous Falcons offense? Plus, we preview Bills-Rams on Monday Night Football, Eagles-Jaguars in London, Bears-Packers and the rest of the Week 5 slate. We'll also react to Buccaneers-Cowboys, the latest NFL injury news and everything else you need to know heading into Sunday. Subscribe for NFL, fantasy football, dynasty and NFL Draft coverage throughout the 2026 season. Timestamps 00:00 | Starting Soon 10:01 | Wake Up Intro 11:04 | Good Morning & Week 5 Show Introduction 15:26 | NFL Injury News: Eagles, Chargers & More 21:45 | Lamar Jackson Injury & Week 5 Updates 23:30 | Cowboys Collapse Against the Buccaneers 32:00 | CeeDee Lamb vs. Zay Flowers Fantasy Bet 34:43 | Eagles vs. Jaguars: Can You Trust Jalen Hurts? 39:24 | Raiders vs. Patriots: Drake Maye & Fantasy Outlook 45:04 | Bears vs. Packers: NFC North Fantasy Matchups 51:56 | Browns vs. Jets: Denzel Boston & Quinshon Judkins 57:17 | Vikings vs. Saints: Can Minnesota Stay Undefeated? 1:05:16 | Colts vs. Steelers: Daniel Jones & Tyler Warren Concerns 1:11:16 | Fantasy Football Start/Sit Questions 1:12:23 | Break 1:15:27 | Texans vs. Titans: Carnell Tate & Nico Collins 1:19:50 | Giants vs. Commanders: Jayden Daniels Returns 1:22:36 | Broncos vs. Chargers: Bo Nix & Justin Herbert 1:27:02 | Lions vs. Cardinals: Fantasy Football Shootout? 1:34:26 | 49ers vs. Seahawks: NFC West Showdown 1:36:20 | Ravens vs. Falcons: Lamar Injury & Derrick Henry 1:41:00 | Bills vs. Rams: Monday Night Football Predictions 1:43:00 | Final Thoughts & Show Wrap-Up 👑 For Access to our Premium Tools (Trinity, WAR & More) & Discord Community https://ddfantasyfootball.com/subscri... Subscribe to the WAKE UP Podcast Feed so you can listen on the Go: 🎙 Spotify: https://spoti.fi/36kkFL8 🍎 Apple: https://apple.co/3GORJra 📺 Subscribe to the Fantasy YouTube Channel DDFFB    / @ddffb   😈Check out All of Ray’s Articles at Yahoo!: https://sports.yahoo.com/author/ray-g... 🏈 Follow Ray on Bleacher Report: https://br.app.link/7ExIDsWfHVb 🅧 Follow us on X: https://x.com/RayGQue https://x.com/ChaboyJRich #NFL #FantasyFootball #NFLWeek5 #NFLLive #FantasyFootballAdvice NFL Week 5, NFL Week 5 Preview, NFL 2026, NFL Week 5 predictions, 49ers Seahawks, 49ers vs Seahawks, Ravens Falcons, Ravens vs Falcons, Lamar Jackson injury, Bills Rams, Bills vs Rams, Eagles Jaguars, Eagles vs Jaguars, Bears Packers, fantasy football Week 5, NFL predictions, Brock Purdy, Josh Allen, Jalen Hurts, Trevor Lawrence, Michael Penix Jr, NFL news, fantasy football, Wake Up, Destination Devy