Medusa (Uma Thurman) - All Scenes Powers | Percy Jackson & the Olympians

'Percy Jackson & the Olympians: The Lightning Thief (2010)' Medusa (Uma Thurman) - All Scenes Powers & Abilities Medusa is a supporting antagonist in the novel Percy Jackson and the Olympians: The Lightning Thief, and its 2010 film adaptation of the same name. She is one of the three guardians of Persephone's Pearls, along with the Hydra and the Lotus Eaters. Portrayed by: Uma Thurman