The Role of CHRNA2 in Nicotine-Enhanced Hippocampal Learning | Podcast #14

In the 14th episode of The Translational Addiction Podcast, we look at how genetics, sex, and adolescent brain development can shape the brain’s response to nicotine. The discussion examines adolescent female mice carrying a mutation in the CHRNA2 gene, which encodes a subunit of nicotinic receptors involved in learning and memory. Join us as we investigate how a tiny change in a single gene can fundamentally alter the way the brain responds to nicotine, and why the same drug dose can strengthen learning in one brain while leaving another unchanged. translationaladdictionpodcast.carrd.co