Overview of the Human Genome and Genetic Variation - Andrew Sharp, Ph.D.

Objective: Learn fundamental information about the human genome Format: Lecture Outline of the history of the genome and the progression of genomics. Architecture and features of the human – genes, repeats, conserved regions, segmental duplications. The spectrum of genetic variation and methods used to detect them. Analytical approaches for detecting functional variants – Association analysis, linkage, exome and whole genome sequencing.