Lac Operon Explained Easy || Regulation of Gene Expression
Biochemistry Basics by Dr Amit
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Lac Operon Explained Easy || Regulation of Gene Expression
21 210 просмотров · 5 лет назад
Biochemistry Basics by Dr Amit
110 тыс. подписчиков
21 210 просмотров · 5 лет назад
This is the video on Lac Operon Concept with NEET PG MCQs. Regulation of gene expression in prokaryotes occur by Lac Operon
00:00 - Introduction
01:52 - Regulation of gene expression in prokaryotes
02:22 - Lac Operon Definition
02:57 - Lac Operon Structure
04:49 - Lac Operon Regulation
05:29 - Lac Operon Regulation in presence of glucose and absence of lactose
06:49 - Lac Operon Regulation in presence of lactose and absence of glucose
07:58 - Lac Operon Regulation in presence of both glucose and lactose
10:28 - NEET PG MCQs
Gene expression is the combined process of the transcription of a gene into mRNA and its translation into protein.
Genetic mutation alter the regulation or expression of gene and results in dysfunctional or non-functional protein synthesis
Information, encoded in DNA, is transcribed into RNA and then translated into protein. It is called the gene expression.
Thus, gene is expressed in terms of synthesis of protein.
Regulation of gene expression in prokaryotes
In prokaryotes, the genes involved in a metabolic pathway are often present in a linear fashion, called an operon. For example:
Lactose operon (Lac operon for regulation of lactose metabolism)
Galactose operon (Gal operon for regulation of Galactose metabolism)
Lactose operon or lac operon
Jacob and Monod in 1961, described operon model for the regulation of lactose metabolism by the intestinal bacterium E.coli.
Definition of Lac Operon
Lac operon is a coordinated unit of gene expression to make the enzymes necessary to metabolize lactose.
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