SwissDrugDesign a free web based environment for docking, virtual screening, target prediction and

Recording of September 2017 AMG Global Health Compound Design webinar presented by Antoine Daina and Vincent Zoete from the Swiss Institute of Bioinformatics. Their second visit covered Ligand-based design, target identification, SwissDock and Swiss Bioisostere Timeline: Start - 1:09 Introduction - Caroline Low, AMG 1:10 - 21:10 Introduction to SwissDrugDesign Project - Vincent Zoete, SIB 2:34 Structure based docking 6:59 Ligand-based CADD 9:15 Swiss Similarity for virtual screening 14:36 Swiss Target Prediction 19:53 Integrated Tools 21:10 - End Live demonstration from Antoine Daina, SIB An exercise with a fictitious phenotypic screening hit 21:10 Finding other compounds to test using Swiss Similarity with fingerprints 32:22 and by 3D similarity 36:00 Target prediction for phenotypic hits 40:00 Extension to malaria targets using protein homology 42:00 Using SwissDock to visualise interaction with protein 52:00 Swiss Bioisoster - what could I make next, 1:01:00 - End Q&A session