49ers vs. Rams Preview, Injury News, Prediction, Analysis, Keys To Game For NFL Week 1

San Francisco 49ers vs. Los Angeles Rams matchup preview presented by Chase Senior of the 49ers report. Sign up for PrizePicks with code: HMA and get $150 in bonus lineups if you win your first $5+ lineup! https://link.prizepicks.com/LME0/CHAT. The Rams had a busy offseason, adding players like Myles Garrett, Jaylen Watson, and Trent McDuffie. However, Chase breaks down why the 49ers can win this game despite being the underdogs. Subscribe for 49ers news, rumors, trade rumors, and free-agency updates:    / @49erstv   Notes on the 49ers: Health & age are big concerns OL once again is an issue Purdy can have a huge year Niners depth is better than 2025 Elite coaching gives you a chance Notes on the Rams: High-end talent extraordinary Garrett & Donald is fascinating Stafford reigning MVP, but old Secondary completely rebuilt LB play and team depth is iffy Mega fan? Prove it — share this episode. New NFL channel from Chase Senior is live. Subscribe for breaking news, hot takes, game reactions, and more:    / @chasedownshow   Chat Sports socials: Twitter:   / chatsports   Facebook:   / chatsports   Hit LIKE if the 49ers are your team. Don't miss out on more of these 49ers videos too: 🚨JUST IN: San Francisco 49ers Get BIG BREAKING News While Traveling To Australia | Nick Bosa News:    • 🚨JUST IN: San Francisco 49ers Get BIG BREA...   🚨49ers Fans Get MASSIVE NEWS + 49ers Need To Make This Huge Trade!:    • 🚨49ers Fans Get MASSIVE NEWS + 49ers Need ...   🚨49ers Could Be Getting A HUGE GIFT Thanks To Rams Going Into Week 1 + 49ers Sign Four More Players:    • 🚨49ers Could Be Getting A HUGE GIFT Thanks...   NOTI GANG — spam “49ers” so we see who showed up first. Follow Chase: Instagram:   / chase_senior   TikTok:   / chase_senior   Facebook:   / chaseseniorchatsports   Full NFL, NBA, and MLB coverage: subscribe to Chat Sports.    / @chatsports   #49ers #49ersNews #49ersRumors #CSPP2026 #ad #CSB