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What If You Had Zero Pain

Superhumanish

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What If You Had Zero Pain

11 просмотров · 8 дней назад
Superhumanish
9 подписчиков
11 просмотров · 8 дней назад
What if you never felt pain — not once? You'd laugh off injections, shrug off a kick to the shin, and grab a hot pan without flinching. But your body would still burn, still break… and nothing would ever warn you. Then comes a stunt on a frozen lake, and a choice between €10,000 and your little sister. Leo's story is fiction. The condition is real. At the end we look at the actual science of people born unable to feel pain. ⏱️ CHAPTERS 0:00 Nothing hurts 1:11 What if you had zero pain? 2:07 The damage you can't feel 2:34 Mr. Black's offer 2:56 The cost nobody mentions 3:37 Mia's system 4:09 Stunt day on the frozen lake 4:59 The crack 6:15 The glove comes off 6:38 That night 6:53 Is any of this real? 7:43 The email 🔬 SOURCES & FURTHER READING • SCN9A and congenital insensitivity to pain (2006): Cox JJ et al. "An SCN9A channelopathy causes congenital inability to experience pain." Nature 444, 894–898 (2006). https://doi.org/10.1038/nature05413 • Loss of smell in the same condition: Weiss J et al. "Loss-of-function mutations in sodium channel Nav1.7 cause anosmia." Nature 472, 186–190 (2011). https://doi.org/10.1038/nature09975 • The Scottish woman who barely feels pain (2019): Habib AM et al. "Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity." British Journal of Anaesthesia 123(2), e249–e253 (2019). https://doi.org/10.1016/j.bja.2019.02.019 • Judging other people's pain: Danziger N, Prkachin KM, Willer JC. "Is pain the price of empathy? The perception of others' pain in patients with congenital insensitivity to pain." Brain 129(9), 2494–2507 (2006). https://doi.org/10.1093/brain/awl155 • Why heat starts to hurt around 43°C: Caterina MJ et al. "The capsaicin receptor: a heat-activated ion channel in the pain pathway." Nature 389, 816–824 (1997). https://doi.org/10.1038/39807 • Cold-water immersion (the "1-10-1" principle): Giesbrecht GG. "Cold stress, near drowning and accidental hypothermia: a review." Aviation, Space, and Environmental Medicine 71(7), 733–752 (2000). 📝 A note on accuracy: the 2019 patient is Jo Cameron, and her pain insensitivity comes from a different gene (FAAH-OUT), not SCN9A. Numbers like "30 meters per second" and "about 43 degrees" are typical values that vary between people. Real cold-water survival depends on many factors. Never test it. 💬 Would YOU switch off your pain? Tell us in the comments, and tell us which superpower we should do next. 🔔 Subscribe for Part 2. #WhatIf #Superpowers #Science #Animation #CongenitalInsensitivityToPain