Do Anti-Amyloid Drugs Leqembi (lecanemab) & Kisunla (donanemab) Work? The Cochrane Review Explained

The Cochrane Review on anti-amyloid Alzheimer's drugs just dropped — and the headline says they don't work. But what does that actually mean? And more importantly, what does it mean for YOU? In this episode, I walk you through the hierarchy of evidence — the critical thinking tool that tells you whether a study, a headline, or a viral health claim is worth acting on — and then I apply it directly to the Cochrane Review. 📥 Download the free RESTORED Protocol for the essential 8 evidence-based lifestyle factors for brain health at moxie-club.com/restored IN THIS EPISODE, we discuss: ✦ What the hierarchy of evidence is and how to use it in real life ✦ 9 key research terms — including correlation vs. causation, confounding variables, and absolute vs. relative risk — and what it means when someone uses them correctly (or doesn't) ✦ Why decades of studies said moderate drinking protects your heart — and why that turned out to be wrong (the UK Biobank story) ✦ What the Cochrane Review (April 2026) actually found about anti-amyloid drugs — and what it didn't say ✦ The AHEAD trial — and why the research world moving earlier is actually good news for prevention ✦ What the highest-quality evidence actually says about preventing Alzheimer's right now RECOMMENDED EPISODES: 👉 Ep 336: APOE4, GLP-1s, and Alzheimer's Risk —    • APOE4, GLP-1s, and Alzheimer's Risk: Hope,...   👉 Ep 314: Does The Brain Eat Itself During Menopause? —    • Does The Brain Eat Itself During Menopause...   REFERENCED in this episode: ● Cochrane Review: Monoclonal antibodies for Alzheimer's disease (published April 16, 2026): https://doi.org/10.1002/14651858.CD01... ● UK Biobank studies on alcohol and cardiovascular/brain health: https://www.ukbiobank.ac.uk/research-... ● AHEAD 3-45 Trial (lecanemab in preclinical Alzheimer's): https://pmc.ncbi.nlm.nih.gov/articles... ● FINGER Study: https://fbhi.se/the-finger-study/ ● U.S. POINTER Study: https://uspointer.net/home.cfm ● Lancet Commission Report on Dementia Prevention 2024: https://www.thelancet.com/journals/la... ● Ornish-Tanzi lifestyle trial: https://pmc.ncbi.nlm.nih.gov/articles...