Advances in the Synthetic Utility of Titanium Methylidene - Dr. Tyler Weinhold [PBC-S01EP02]

In this episode Dr. Tyler Weinhold gives a talk about Titanium Methylidene generated by Tebbe's reagent. He discuss recent studies involving Tebbe’s reagent in dibromination and cyclopropanation, as well as its application in the enantioselective total synthesis of (+)-fusicoccadiene, recently published in JACS. Main publications: Enantioselective Synthesis of (+)-fusicoccadiene: https://pubs.acs.org/doi/10.1021/jacs... Access to 3-azetidines via Halogenation of Titanacyclobutanes: https://advanced.onlinelibrary.wiley.... Direct ketone cyclopropanation enabled by Tebbe's reagent: https://www.sciencedirect.com/science... Suggested youtube channels: NileRed: / @nilered Synthesis Workshop: / @synthesisworkshopvideos Simplifying synthesis: / @simplifyingsynthesis Total Synthesis: / @totalsynthesis