Standardizing CIDP Care: New Consensus Definitions & Emerging Therapies

Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare, immune-mediated peripheral nerve disease that presents significant challenges in both diagnosis and long-term care. In this follow-up discussion, Dr. Karissa Gable, Professor of Neurology at Duke University Medical Center, shares key updates in the field that have occurred since the launch of her recent educational activity. She discusses a new international consensus definitions paper that establishes standardized terminology for clinical concepts like remission and refractory disease, reviews the expanding pipeline of emerging FcRn antagonists and complement inhibitors, and highlights why shared decision-making remains vital throughout the patient journey. Read the full accompanying article on Full Stack Med: https://fullstackmed.com/cidp-faculty... Earn CME contact hours by completing the ‪@i3health‬ educational activity: https://bit.ly/4i4xxpz What You’ll Learn in This Episode: 🔹 Standardizing the Language of CIDP: Understanding how the new international consensus paper defines remission, stability, treatment response, and refractory disease to improve trial design and clinical care. 🔹 A Growing Pipeline of Emerging Therapies: Evaluating investigational agents in development, including FcRn antagonists like batoclimab and nipocalimab, as well as ongoing studies of complement inhibitors. 🔹 The Search for Serologic Biomarkers: Exploring the clinical need for improved biomarkers to strengthen diagnostic accuracy and guide long-term treatment management. 🔹 Shared Decision-Making in Neuromuscular Care: Taking a personalized approach to treatment by aligning clinical efficacy with patient lifestyle, comorbidities, and route of administration preferences. 🔹 Building Confidence in Practice: Leveraging the comprehensive educational activity to master CIDP management, from 2021 EAN/PNS guidelines to current and emerging treatment algorithms. Chapter Timestamps: 00:00 – Introduction: The Evolving CIDP Landscape 01:00 – Standardizing the Language: New Consensus Definitions 02:15 – The Emerging Treatment Pipeline & Biomarkers 03:30 – Practical Applications of Shared Decision-Making 04:45 – Masterclass Overview & Guideline-Directed Care 05:30 – Outro & CME/CNE Educational Activity Details About the Speaker: Karissa Gable, MD, is a Professor of Neurology at Duke University Medical Center in Durham, North Carolina. She specializes in the treatment of chronic inflammatory demyelinating polyneuropathy (CIDP), amyloid polyneuropathy, hereditary neuropathy, and peripheral neuropathy. Dr. Gable is actively involved in clinical trials as well as education training for medical students, residents, and fellows. Stay Connected: Subscribe for more deep dives into clinical neurology and medical education. Website: https://fullstackmed.com/ #CIDP #Neurology #RareDisease #Neuromuscular #MedicalEducation #CME #CNE #i3Health #FullStackMed #SharedDecisionMaking #PatientCare #research #education #motivation #medical #medicine #medicalstudents #medicaleducation #meded #foryou #foryoupage #fyp #duke #neuropathycare