Long Covid Associated with Elevated Interferon Levels

Roger Seheult, MD of MedCram explores elevated interferon levels associated with long covid. See all Dr. Seheult's videos at: https://www.medcram.com/ (This video was recorded on February 23rd, 2024) Roger Seheult, MD is the co-founder and lead professor at https://www.medcram.com/ He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine. LINKS / REFERENCES: Spontaneous, persistent, T cell–dependent IFN-γ release in patients who progress to Long Covid (Science Advances) | https://www.science.org/doi/10.1126/s... Viruses and interferon: a fight for supremacy (Nature) | https://www.nature.com/articles/nri888 Interferon Responses Could Explain Susceptibility to Severe COVID-19 (Medium) |   / interferon-responses-could-explain-suscept...   Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients (Science) | https://www.science.org/doi/10.1126/s... Examination of autoantibodies to type I interferon in patients suffering from long COVID (Journal of medical virology) | https://pubmed.ncbi.nlm.nih.gov/37698... SARS-CoV-2 Mac1 is required for IFN antagonism and efficient virus replication in cell culture and in mice (PNAS) | https://www.pnas.org/doi/10.1073/pnas... Early Treatment with Pegylated Interferon Lambda for Covid-19 (NEJM) | https://www.nejm.org/doi/full/10.1056... Hyperthermia in humans enhances interferon-gamma synthesis and alters the peripheral lymphocyte population (Journal of interferon research) | https://pubmed.ncbi.nlm.nih.gov/3132509/ The biological activity of interferons in post-COVID syndrome (ERJ) | https://openres.ersjournals.com/conte... Prevalence of persistent SARS-CoV-2 in a large community surveillance study (Nature) | https://www.nature.com/articles/s4158... Interferon Response in Hepatitis C Virus-Infected Hepatocytes: Issues to Consider in the Era of Direct-Acting Antivirals (International journal of molecular sciences) | https://www.ncbi.nlm.nih.gov/pmc/arti... Treatment of hepatitis C virus infection with interferon and small molecule direct antivirals: viral kinetics and modeling (Critical reviews in immunology) | https://www.ncbi.nlm.nih.gov/pmc/arti... SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL: https://www.youtube.com/user/MEDCRAMv... to a more unhealthy diet impacts sleep microstructure during normal sleep and recovery sleep: A randomized trial=1 Get notified of new videos by hitting the bell icon MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS: MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested. MEDIA CONTACT: Media Contact: customers@medcram.com Media contact info: https://www.medcram.com/pages/media-c... Video Produced by Kyle Allred Edited by Daphne Sprinkle of Sprinkle Media Consulting, LLC FOLLOW US ON SOCIAL MEDIA:   / medcram     / medcramvideos     / medcram   DISCLAIMER: MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor. #covid19 #interferon #coronavirus