Understanding iNAP: Oral Sleep Apnea Therapy

Dr. Weiner reviews the clinical evidence and discusses where oral pressure therapy may be an option for treating obstructive sleep apnea. In Unmasked: Beyond CPAP, we explore CPAP alternatives available in 2026. From hypoglossal nerve stimulation (Inspire and Genio) to oral appliances, positional therapies, and minimally-invasive surgeries, we review the medical research to help you understand your options. Dr. Weiner is a board-certified ear, nose, and throat doctor in Scottsdale, Arizona, with over 20 years of experience in treating people who struggle with CPAP. His mission is to help you find a treatment you can stick to, so you can enjoy better sleep and health. He is licensed in 31 states and is available for consultation in person and via telemedicine. For more information about CPAP alternatives and Dr. Weiner's practice, visit https://weinersleepsurgery.com/ Studies referenced in this video: Nilius G, Farid-Moayer M, Lin CM, Knaack L, Wang YP, Dellweg D, Stoohs R, Ficker J, Randerath W, Specht MB, Galetke W, Schneider H; iNAP Study Group. Multi-center safety and efficacy study of a negative-pressure intraoral device in obstructive sleep apnea. Sleep Med. 2024 Jul;119:139-146. doi: 10.1016/j.sleep.2024.04.015. Epub 2024 Apr 17. PMID: 38678757. Puvatanond C, Kasemsuk N, Banhiran W. The efficacy and safety of an intraoral negative air pressure device in patients with obstructive sleep apnea: a systematic review and meta-analysis. J Clin Sleep Med. 2025 Nov 1;21(11):1969-1977. doi: 10.5664/jcsm.11812. PMID: 40605357; PMCID: PMC12582209. Product webite: https://inapsleep.online/ Unmasked: Beyond CPAP is for general informational purposes only and does not constitute the practice of medicine; no doctor/patient relationship is formed. Relying on information provided through this channel is solely at your risk. While efforts are made to be accurate, information may change. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. See a health care professional for any medical condition you may have. Dr. Weiner is a member of the Inspire Physician Advisory Council and an instructor at physician educational and training activities for Inspire Medical Systems for which he is compensated. 0.00 Introduction 0.37 What is oral pressure therapy? 1.04 What is the iNAP Sleep System? 1.45 The "Mouth Vacuum" 2.10 Does oral pressure therapy with iNAP work? 3.49 Whose sleep apnea may improve using iNAP? 4.04 Is iNAP as effective as CPAP or surgery? 4.10 Is iNAP a nonivasive alternative to CPAP? 4.13 Any side effects with iNAP? 4.24 What is the maintenance? 4.32 Does insurance cover iNAP? 4.57 In summary