Adrenergic and Antiadrenergic Drugs 4, Karmalawy

1) Neuronal Blocking Agents (act on the neuron) (1) Guanethidine Sulfate (2) Bretylium Tosylate 2) Receptor Blockers (α- and β-blockers) α-Adrenergic Blocking Agents a) β-Haloalkylamines: (Nonselective α-adrenergic blockers (Irreversible blockers)) (1) Phenoxybenzamine hydrochloride b) Imidazolines as non-selective α-adrenergic blockers (Reversible blockers) (1) Tolazoline Hydrochloride c) Selective α1–Antagonists: (Reversible Blockers) Azosins (quinazoline-containing compounds) (1) Prazosin Hydrochloride (2) Terazosin Hydrochloride Uroselective α1-Blockers (Tamsulosin and Alfuzosin) β-Adrenergic Blocking Agents Non-Selective β-Blockers (1) Propranolol HCl (2) Nadolol (3) Pindolol β1-Selective Blockers (1) Metoprolol bitartrate (2) Bisoprolol (3) Atenolol (4) Acebutolol β-adrenergic antagonists used in the treatment of chronic open-angle glaucoma (1) Timolol maleate (2) Betaxolol HCl Drugs affecting NE/E biosynthesis (1) Methyldopa (2) Carbidopa Structure-Activity Relationships (SAR)