Kahler's Disease, Causes, Signs and Symptoms, Diagnosis and Treatment.

. Chapters 0:00 Introduction 0:38 Symptoms 1:18 staging kahler disease 2:28 Treatment • Kahler’s disease, also known as multiple myeloma, is a blood cancer that occurs in the plasma.  • In the disease, the body’s bone marrow is affected, and cancerous cells begin to replace the healthy blood cells.  • It is the most common type of Myeloma and is considered to be the 14th most common kind of cancer in the world.  • The effects of cancer can also reach your kidneys due to the development of abnormal proteins.  • Kahler’s disease thus tends to affect different parts of the body.  Here’s everything you need to know about it:  Symptoms  • As Kahler’s disease starts with the bone marrow, the bones experience the most typical symptoms of the disease.  • Pain in the bones is one common indication.  • More than that, the bones can even break if the condition spreads unchecked.  • However, since the disease spreads to different parts of the body, you are likely to experience a host of other symptoms, such as:  • Nausea • Excessive thirst  • Frequent fevers and infections  • Weight loss • Urinating excessively  • Constipation  Staging Kahler’s Disease  • Staging cancer means determining the spread and growth of cancer in the human body.  • Staging for multiple myeloma can be done using the International Staging System (ISS) or the Durie-Salmon system.  • The latter checks the amount of calcium inside the blood along with proteins such as monoclonal immunoglobin and hemoglobin.  • The initial stage is the smoldering stage, in which the myeloma does not cause active symptoms. This cancer exists but has not spread enough to cause problems.  • Stage 1 Kahler’s will show a small number of cancerous cells in the urine and blood.  • Hemoglobin levels are just slightly lower in this stage, while a bone X-ray would be clear or show just one affected area.  • Stage 2 is far more serious, with increased monoclonal immunoglobin and calcium, while hemoglobin will show a significant decrease.  • Furthermore, stage 2 Kahler’s may also cause extensive bone damage.  • Stage 3 is the most advanced stage of multiple myeloma, characterized by very low hemoglobin and very high amounts of calcium.  • The body shows multiple signs of damage.  Treatment • The treatment of Kahler’s disease depends on the stage of cancer.  • Typical treatments for it include radiation, chemotherapy, and plasmapheresis, a blood treatment.  • In some cases, bone marrow or stem transplant may be necessary.  • However, the treatments cannot cure Kahler’s.  • The cancerous cells may decrease in numbers and the symptoms may go away only to recur at another time.  • The recurrence makes living with Kahler’s disease incredibly difficult, and regular checks and significant lifestyle changes have to be made.