Thalassemia (Alpha & Beta) | Pathology | Genetics & NESTROFT Test | Dr. Priyanka Sachdev

Complete guide to Thalassemia (Quantitative Hemoglobinopathy) for 2nd Prof MBBS, NEET PG, and FMGE. In this lecture, Dr. Priyanka Sachdev explains the difference between Qualitative (Sickle Cell) and Quantitative (Thalassemia) globin disorders, the molecular genetics of Alpha vs. Beta Thalassemia, and the NESTROFT screening test. 📝 Topics Covered: ✅ Introduction: Hemoglobin A (2α2β), F (2α2γ), A2 (2α2δ). ✅ Classification: Qualitative vs. Quantitative Hemoglobinopathies. ✅ Beta Thalassemia: Chromosome 11 (Point Mutation). Major (Cooley's Anemia): Severe anemia, Chipmunk Facies, Hair-on-end appearance. Minor/Trait: Asymptomatic. ✅ Alpha Thalassemia: Chromosome 16 (Deletion). Hb H Disease (3 genes deleted). Hydrops Fetalis (4 genes deleted - Hb Barts). ✅ Lab Diagnosis: Microcytic Hypochromic Anemia, Target Cells, NESTROFT Test (Naked Eye Single Tube Red Cell Osmotic Fragility Test). ✅ Management: Blood Transfusion & Iron Overload. ----------------------------------------------------------------------- 🚀 Ace Your MBBS Exams with Our Premium Courses 📚 2nd Prof Buster 2.0 (Pathology, Pharmacology, Microbiology) 👉 [https://courses.medlivebydrpriyanka.c...] 📚 3rd Prof Buster 1.0 (PSM, ENT, Ophthalmology) 👉 [https://courses.medlivebydrpriyanka.c...] 📥 Download the App for Full Access: [https://courses.medlivebydrpriyanka.com] #MedLive #DrPriyankaSachdev #Pathology #Thalassemia #Hematology #Anemia #BetaThalassemia #AlphaThalassemia #NESTROFT #MBBS #NEETPG #FMGE