12. Mechanism of Enzyme Action | Lock & Key Model, Induced fit, substrate strain, MOA catalysis

This video is the part of playlist:    • Enzyme   Link to download PDF notes of this video: https://drive.google.com/file/d/1_tTG... ************************************** Link of Next video: [Will be added soon] Link of previous video:    • 11 B.  Enzyme Inhibition (Part – 2 of 2) |...   ************************************** Mechanism of Enzyme Action – Lock & Key Model, Induced Fit, Catalysis Explained! 🧪🔬 📌 In this video, you’ll learn: How enzymes catalyze reactions by lowering activation energy (ΔG‡). 3 models of enzyme-substrate binding: Fischer’s Lock & Key, Koshland’s Induced Fit, and Substrate Strain Theory. 4 mechanisms of enzyme catalysis: Acid-Base, Covalent, Proximity, and Strain Catalysis. Real-world examples (e.g., Serine Proteases, Lysozyme, Ribonuclease). 📖 Detailed Breakdown: 1️⃣ Energy Changes in Reactions: Transition states, activation energy, and how enzymes speed up reactions without altering equilibrium. 2️⃣ Enzyme-Substrate Complex Formation: Fischer’s Template Theory (1894): Rigid active sites & specificity. Koshland’s Induced Fit (1958): Flexible enzymes & conformational changes. Substrate Strain Theory: Enzyme-induced substrate destabilization. 3️⃣ Catalysis Mechanisms: How amino acid side chains (e.g., Histidine, Serine) facilitate reactions. 🔥 Key Questions Answered: Why doesn’t an enzyme change ΔG of a reaction? What’s the difference between lock-and-key vs. induced fit? How do allosteric regulators affect enzyme action? **************************************** mechanism of enzyme action mechanism of enzyme action biochemistry mechanism of enzyme catalysis mechanism of enzyme mechanism of enzyme action in hindi mechanism of enzyme action bsc 2nd year mechanism of enzyme action taking trypsin as example mechanism of enzyme inhibition mechanism of enzyme action notes mechanism of enzyme reaction mechanism of enzyme action lock and key model mechanism of enzyme action in tamil mechanism of enzyme action trypsin mechanism of enzyme catalysis in hindi ************************************** Index: 00:00 – Introduction 01:25 – Energy changes in reaction 09:18 – Fischer’s Templet theory 12:18 – Koshland’s Induced Fit theory 14:17 – Substrate Strain Theory 16:15 – 4 Catalysis Mechanisms (Acid-Base, Covalent, Proximity, Strain) #EnzymeMechanism #Biochemistry #LockAndKeyModel #InducedFit #EnzymeCatalysis #BiologyTutorial #ScienceEducation #STEM #biochemistry #neet #mbbs #csirnet #usmle #enzyme #catalysis