Advancing Spatial Biology — AACR 2025 Highlights with Chakra Chennubhotla & Arutha Kulasinghe
PredxBio Inc.
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Advancing Spatial Biology — AACR 2025 Highlights with Chakra Chennubhotla & Arutha Kulasinghe
124 просмотра · 1 г. назад
PredxBio Inc.
29 подписчиков
124 просмотра · 1 г. назад
Join us for highlights from AACR 2025, where S. Chakra Chennubhotla, PhD (Co-Founder & Chief of AI, PredxBio) and Arutha Kulasinghe, PhD (University of Queensland) share how SpaceIQ™, our explainable AI-driven spatial multiomics platform, is uncovering new biology behind immune response and resistance in cancer.
In this session, Chakra discusses how SpaceIQ™ enables robust hypothesis generation and verification, advanced cell segmentation, and emergent microdomain mapping to reveal real mechanistic insights. Arutha shares real-world clinical studies in lung, head & neck, and colorectal cancers, showing how minimal spatial biomarker signatures can predict response to checkpoint inhibitor therapy — and what this means for the future of precision oncology.
🔬 Key Topics:
Hypothesis-free, unbiased spatial analytics
Microdomain discovery and cell-cell communication
Overcoming fibrosis barriers in immunotherapy
Defining minimal multi-marker signatures
Bridging discovery to clinical deployment
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