Flexomics: Advancing Single-Cell Biology with Integrated Imaging and Sequencing

Single-Cell Sequencing Meets Live-Cell Imaging | Flexomics Platform Explained How can cellular phenotypes be directly linked to their underlying molecular states? In this video, Magali Soumillon, PhD, Co-founder and CEO of Flexomics, introduces an innovative single-cell multi-omics platform that connects live-cell functional imaging with sequencing readouts from the same individual cells. This breakthrough approach enables researchers to capture both cell behavior and molecular profiles in a single workflow, opening new possibilities in genomics, immunology, and cancer research. 🔬 Key Features: Integrated single-cell analysis combining imaging and sequencing Picowell-based platform with optically encoded barcoded beads Simultaneous measurement of cellular phenotypes, gene expression, and immune receptor sequences Seamless workflow for multi-omics data generation and analysis 🧬 Applications: Immune profiling, including T cell receptor (TCR) identification Drug response analysis in adherent cancer cells Advanced studies linking cell function to transcriptomic states By bridging live-cell imaging with single-cell sequencing, the Flexomics platform enables experimental designs that are not possible with traditional methods. This work is supported by the NIH SBIR program, including the National Human Genome Research Institute (NHGRI) and the National Cancer Institute (NCI). 🌐 Learn more: https://flexomics.com 📧 Contact: info@flexomics.com #singlecell #technology #genomics #NHGRI #NCI 00:00 - Introduction 00:46 - Connecting live-cell imaging with molecular readouts 04:54 - FLXplorer: Data analysis 06:32 - Application 08:11 - NIH SBIR Support 08:52 - Future Directions Remember to like 👍, subscribe, and hit the notification bell 🔔to stay updated on our latest content! Disclaimer: Genome TDCC does not endorse or recommend any commercial products or services. Inclusion of a speaker's views or opinions on our channel does not constitute endorsement by Genome TDCC, The Jackson Laboratory (JAX), National Human Genome Research Institute (NHGRI), or the U.S. Government. Reference herein to any specific commercial product, process, or service by trade name, trademark, manufacturer, or otherwise, does not constitute or imply its endorsement, recommendation, or favoring to the exclusion of other available products, processes, or services.