Dihybrid Crosses and Pedigrees and Inheritance | Six Minutes: Biology, Part 17
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Dihybrid Crosses and Pedigrees and Inheritance | Six Minutes: Biology, Part 17
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Six Minutes: Biology, Part 17: Dihybrid Crosses and Pedigrees and Inheritance: Solve two-trait crosses step by step; then Pedigrees and Inheritance
A dihybrid cross tracks two genes at once, using four gamete types and a sixteen-box Punnett square. Heterozygous-by-heterozygous crosses give the classic 9:3:3:1 phenotype ratio, which you can verify by multiplying single-trait probabilities. Then: Learn the symbols of a pedigree and the two questions that reveal whether a trait is dominant or recessive, autosomal or X-linked. Then assign genotypes from a family chart and check them with a Punnett square.
Chapters
0:00 Introduction
0:23 Two genes at once
1:00 The 4 by 4 square
1:43 Worked example
2:33 Trap
2:59 Recap
3:18 Pedigrees and Inheritance
3:30 Reading the symbols
3:52 Spotting the pattern
4:34 Worked example
5:34 The trap
5:56 Recap
6:13 Thanks for watching
Practice problems
1. In a made-up plant, gene T controls height (T = tall, t = short) and gene C controls flower color (C = red, c = white). Cross two plants that are both TtCc. What fraction of offspring should be short with white flowers? Answer: 1/16.
2. Cross a TtCc plant with a ttcc plant. List the gametes of each parent and give the phenotype ratio of the offspring. Answer: TtCc makes TC, Tc, tC, tc; ttcc makes only tc; offspring ratio is 1 tall red : 1 tall white : 1 short red : 1 short white.
3. In a pedigree, two unaffected parents have an affected son and an affected daughter. What inheritance pattern fits, and why? Answer: autosomal recessive, because unaffected parents have affected children and both sexes are affected.
4. Two unaffected parents have three children: one affected, two unaffected. If the trait is autosomal recessive, what are the parents' genotypes and the chance an unaffected child is a carrier? Answer: both Aa; two out of three.
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