What If the Medicine Already Exists?

What if a treatment that could change someone’s life already exists, but no one has connected the dots yet? In this episode, Amy Sylvis talks with scientist and Every Cure Chief Scientific Officer Matt Goddeeris about an unconventional approach to drug development: finding new uses for medications that already exist. Matt explains how drug repurposing, artificial intelligence, scientific research, and patient involvement can come together to uncover treatments for diseases that may otherwise receive little attention. Matt shares the remarkable story of Bachmann-Bupp syndrome, an ultra-rare disease affecting only a small number of known patients worldwide, and how an existing drug has helped change the lives of children living with it. The conversation also turns personal as Matt explains why he left traditional biotech for nonprofit work, how financial security gave him the freedom to make that decision, and why thinking more about money can sometimes be a signal that something deeper is missing from your work. Connect with Matt Goddeeris:  matt@everycure.org Connect with Amy Sylvis:   / amysylvis   Contact Us: https://www.sylviscapital.com https://www.sylviscapital.com/webinar info@sylviscapital.com 00:00 Getting to Know Matt Goddeeris 02:55 From Scientific Curiosity to Finding New Uses for Existing Drugs 07:37 Using AI to Connect the Dots Between Drugs and Diseases 10:56 Why Patients Need a Voice in the Research 13:03 How an Existing Drug Changed Lives With an Ultra-Rare Disease 19:19 Leaving Traditional Biotech for More Purposeful Work 22:59 Building Financial Security Before Making a Career Pivot 27:20 Maximize Each Day Doing What You Enjoy