Unlocking Comprehensive Genomic Insight: Clinical Blended Genome-Exome Sequencing in Practice

To realize the full impact of precision medicine across diverse populations, clinicians and researchers often face a difficult choice: Conduct studies leveraging the comprehensive breadth of Whole Genome Sequencing (WGS) or focus on the targeted depth achievable with Whole Exome Sequencing (WES). Clinical Blended Genome-Exome (cBGE) sequencing emerges as a transformative solution, combining both sequencing approaches into a single, highly scalable workflow. This session explores the technical mechanics behind this approach—utilizing low-coverage, PCR-free WGS coupled with high-depth WES on high-throughput platforms like the NovaSeq X Plus. By leveraging DRAGEN-powered informatics to deliver a unified suite of outputs, including CRAM files, VCFs, and CNV calls, this method provides superior genomic visibility without the traditional overhead of separate assays. Join Broad Clinical Labs and a panel of distinguished clinical and research leaders for an in-depth exploration of how cBGE is redefining genomic inference and its impact on public health. This webinar explores technical theory and showcases real-world applications—including Heartgene’s Everygene program for expanding national access to cardiovascular genetic testing and the VA ProGRESS Study’s use of cBGE to power integrated risk models (P-CARE) for prostate cancer screening in Veterans. Participants will gain insight into a proven model for integrating testing, interpretation, and counseling to drive both patient and provider engagement at scale. 0:00 Introduction 2:38 Niall Lennon 31:00 Megan Sutton 49:05 Charles Brunette 57:13 Morgan Danowski 105:47 Q&A - - - - - - - - - - - - - - - - - - - - ABOUT SAMBA SCIENTIFIC Samba Scientific is a leading life science and biotech marketing agency specializing in innovative and data-driven marketing services tailored to the life sciences and biotechnology sectors. Our team of experts understands the industry's unique challenges and delivers strategic solutions that drive engagement, growth, and brand visibility. Whether launching a new product, expanding your reach, or enhancing your digital presence, Samba Scientific provides the expertise and creativity to help you succeed. VISIT OUR WEBSITE https://sambasci.com CONNECT WITH US ON SOCIAL MEDIA LinkedIn:   / sambascientific   Instagram:   / sambascientific   Facebook:   / sambascientific   X:   / sambasci   CONTACT US For inquiries and more information, reach out to sales@sambasci.com Don't forget to subscribe for more life science marketing insights and updates! #Biotech #LifeSciences #Pharma #Marketing #LifeScienceMarketing #BiotechMarketing #MarketingAgency #MarketingServices #SambaScientific #STEM #Biology #Science