كيمياء عضوية صيدلانية | Prodrugs Lec.7 Pt.5

شرح (الـ Prodrug موضوع 21) الذي هو من الاضافات الجديدة للمنهج الموحد الخاص بالكيمياء الصيدلانية العضوية Organic Pharmaceutical Chemistry الكورس الثاني للمرحلة الثالثة / كلية الصيدلة قناة التليكرام : https://t.me/muntedher_Alhussainy https://t.me/helixoisensei ما تم شرحه في الفيديو : 00:00 Introduction to Chemical drug delivery 02:41 Factors related to success of site-specific drug delivery 05:55 Routes other than Chemical Delivery Systems for drug delivery 07:59 Basic goal oc site-specific drug delivery 11:26 Example of site-specific chemical drug delivery system to urine (Methanamine) 14:09 Cancer chemotherapy selective delivery to tumor tissue 15:36 Example of site-specific drug delivery require many steps to activation (Capecitabine) 19:34 Antibody Directed Enzyme Prodrug Therapy 23:28 Example of site-specific chemical drug delivery system (Idoxuridine) 28:09 Example of site-specific chemical drug delivery system to Brain (L-dopa) 33:29 Example of site-specific chemical drug delivery system to Brain (Pro-2-PAM) 36:18 Issues of drug delivery across BBB and dihydropyridine derivatives 44:17 Example of site-specific chemical drug delivery system to Eye (Dipivefrin) 45:55 Use of glucosidase to site-specific chemical drug delivery to GIT