Nucleic Acid Chemistry | شرح Nucleic acid بايوكميستري د محمد الكسار

📲 Telegram Channel | Dr. Mohamed Al-Kassar https://t.me/Drelkassarbio Nucleic Acid Chemistry | شرح Nucleic Acid بايوكميستري د. محمد الكسار 🧬 في المحاضرة دي هنشرح Nucleic Acid Chemistry في مادة الـ Biochemistry شرحًا متكاملًا، بدايةً من التركيب الكيميائي للأحماض النووية، مرورًا بالـ Nitrogenous Bases والـ Pentose Sugars والـ Phosphate Groups، وصولًا إلى الـ DNA والـ RNA والـ Nucleotides ومشتقاتها وأهميتها البيولوجية والطبية. 🧬 Lecture Contents | محتويات المحاضرة 🔹 1. Introduction to Nucleic Acids Definition and classification of nucleic acids. Biological importance of nucleic acids. Differences between DNA and RNA. 🔹 2. Components of Nucleic Acids Nitrogenous Bases: Purines and Pyrimidines. Pentose Sugars: Ribose and Deoxyribose. Phosphate Group and its biological importance. N-glycosidic bond and phosphodiester bond. 🔹 3. Nucleosides vs Nucleotides Definition, structure, and differences. Nucleoside and nucleotide formation. Monophosphate, diphosphate, and triphosphate nucleotides. AMP, ADP, ATP, GMP, GDP, GTP, CMP, CDP, CTP, UMP, and UTP. 🔹 4. ATP, GTP, CTP and Other Nucleotide Triphosphates ATP as the energy currency of the cell. GTP in protein synthesis and intracellular signaling. CTP in phospholipid synthesis. UTP in carbohydrate metabolism and glycogen synthesis. High-energy phosphate bonds and energy transfer. 🔹 5. Cyclic Nucleotides: cAMP and cGMP Structure and formation of cyclic AMP (cAMP). cAMP as a second messenger. Role of cAMP in hormone action and signal transduction. Cyclic GMP (cGMP) and its biological functions. 🔹 6. DNA Chemistry Structure and chemical composition of DNA. Double helix and complementary base pairing. A–T and G–C pairing. Phosphodiester bonds and DNA stability. DNA replication and storage of genetic information. 🔹 7. RNA Chemistry Structure and composition of RNA. Differences between DNA and RNA. mRNA, tRNA, and rRNA. Role of RNA in protein synthesis. 🔹 8. Nucleosomes and Chromatin Nucleosome structure and organization. Histone proteins and DNA packaging. Chromatin and chromosome formation. Biological importance of DNA packaging and gene regulation. 🔹 9. Biological Importance of Nucleotides Building blocks of DNA and RNA. Cellular energy transfer. Protein synthesis and metabolic reactions. Intracellular signaling. Nucleotide derivatives and their biological functions. 🎯 Why is Nucleic Acid Chemistry important? فهم الـ Nucleic Acids مش مجرد حفظ أسماء وتركيبات؛ الأهم إنك تفهم العلاقة بين الـ Chemical Structure والـ Biological Function، وتعرف تميّز بين الـ Nucleoside والـ Nucleotide، وتفهم أهمية ATP وGTP وCTP والـ cAMP، وتربط كل جزء بوظيفته داخل الخلية. 📚 Biochemistry | Dr. Mohamed Al-Kassar شرح منظم يساعدك على فهم الـ concepts الأساسية، وربط المعلومات ببعضها، والاستعداد لأسئلة الـ MCQs والامتحانات. 📲 Join the Telegram Channel for Updates and Study Materials: https://t.me/Drelkassarbio #NucleicAcids #Biochemistry #DNA #RNA #Nucleotides #ATP #GTP #CTP #cAMP #Nucleosome #MedicalBiochemistry #شرح_بايوكيميستري #د_محمد_الكسار