Lipidomics & Ceramide Analysis in Skin Research | with Veronika Piskovatska | The Lipidomics Webinar

Skin health and disease is closely related to lipid composition and function in different skin structures. Various factors contribute to variability in skin lipidome and ceramidome. --- OUTLINE This webinar is dedicated to skin lipids and their role in skin health and disease and will discuss lipid composition and function in different skin structures. The webinar will begin with an overview of skin anatomy with a focus on the stratum corneum. The lipidome of normal skin will be discussed next, emphasizing the importance of ceramides. Our scientific talk will focus on the pivotal role ceramides play in skin physiology and their relevance in context of skin research and product claim support. During the webinar, factors contributing to variability in skin lipidome and ceramidome will be discussed, including age, sex, body part, pigmentation, depth of skin sampling, and seasonal differences. Finally, we will examine the alterations in the skin lipidome caused by various pathological conditions, such as xerosis, atopic dermatitis, and psoriasis, and explore the relationship between the skin lipidome and the skin microbiome. --- CHAPTERS 00:00 - Introduction to the anatomy and function of human skin 04:46 - Keratinocyte maturation and differentiation 09:35 - Lipids in stratum corneum and stratum granulosum 14:15 - How to apply lipidomics in dermatological research 19:11 - Variability of the skin's lipid composition 27:48 - How skin pigmentation influences skin ceramide composition 35:00 - The role of ceramides in pathological skin conditions 40:40 - Relationship of dry skin, microbiome, and lipid metabolism --- MORE LinkedIn:   / lipotype   Twitter:   / lipotype_global   Instagram:   / lipotype_global   Facebook:   / lipotype   #lipidomics #webinar #dermatology