This Changes How I Think About Creatine

Can a simple 5g scoop of creatine do more than just build muscle? In today’s video, I’m reacting to Thomas DeLauer’s insights on how creatine might “spare” your body’s methylation cycle—and then diving deep into the actual clinical data to see if it really lowers homocysteine. As a vascular surgeon, I’m always looking for ways to reduce cardiovascular risk. We know that high homocysteine is a major red flag for heart attack and stroke, but the evidence for using creatine to fix it is surprisingly nuanced. In this video, we cover: The "Metabolic Cost" of making your own creatine. How methylation impacts your DNA repair and neurotransmitters. My breakdown of the 2015 Journal of Nutrition study on creatine and homocysteine. Why the "MTHFR mutation" changes the whole conversation. My current stance on methylated B vitamins vs. creatine. Chapters: 0:00 - Reaction to Thomas DeLauer’s Creatine Theory 1:15 - How Creatine Synthesis Drains Your Body 3:02 - The Glycine Connection: Joints, Skin, and Detox 5:42 - Implications for MTHFR and High Homocysteine 8:18 - Does Creatine Lower Homocysteine? (Open Evidence Search) 12:28 - Deep Dive: Bangladesh Randomized Controlled Trial 18:10 - The Verdict: Folic Acid vs. Creatine 21:30 - My Recommendations for Patients Let me know your thoughts on creatine in the comments! Are you taking it for more than just the gym? Do these suggestions align with the direction you want to take for this video? Sign up for more information on my own practice here: https://corsighthealth.com/ High Quality 3rd-party tested supplements at Fullscript (10% discount): https://us.fullscript.com/welcome/ljo... Order your own labs here: https://www.ultalabtests.com/partners... OR www.ownyourlabs.com Other tools for optimal health (note these are affiliate links): Home BP Cuff: https://amzn.to/49Cq7rh Sonicare Toothbrush: https://amzn.to/3KllfMS WaterPik: https://amzn.to/4894Xi8 Apple Watch with sleep & HR monitoring: https://amzn.to/3XaUn5d Oura Ring with sleep, cycle, and recovery monitoring: https://amzn.to/4riyhLS Intake Breathing Nasal Support: https://amzn.to/48dfQQ1 Personal Blender: https://amzn.to/4pyNGGl True Nutrition Protein: https://oken.do/q2xzqeqw Glass Meal Prep Containers: https://amzn.to/4ocEPJ2 Sleep Mask: https://amzn.to/48fSJV5 Air Purifier: https://amzn.to/4puzTQZ ___________________________ 🧬 About Dr. Lily Johnston Dr. Johnston is a double board-certified vascular and general surgeon in San Diego, specializing in metabolic and cardiovascular prevention. She’s the founder of CorSight Health and a passionate advocate for reimagining how medicine approaches chronic disease. #MetabolicHealth #CardiovascularPrevention #HeartHealth #Longevity #InsulinResistance #DrLilyJohnston #DrLily #WomenInMedicine #Surgeon #VascularSurgeon #PreventiveMedicine #PADPrevention #HeartAttackRisks #HealthPortfolio #California #SanDiego #Arizona #Virginia #Minnesota