Structure of Nucleosome | Histone Proteins Chromatin | NEET Class 12 | Neela Bakore Tutorials

◀ PREVIOUS VIDEO (7/26): Structure of rRNA & Important Terms    • Structure of rRNA & Important Terms | Ribo...   ▶ CURRENT VIDEO (8/26): Structure of Nucleosome    • Structure of Nucleosome | Histone Proteins...   ▶ NEXT VIDEO (9/26): Griffith's Experiment of Transformation    • Griffith's Experiment of Transformation | ...   🔗 Full Playlist:    • Плейлист   ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ How does 2 metres of DNA fit inside a tiny nucleus? The nucleosome! This video explains DNA packaging through nucleosomes and chromatin organisation. 📌 Topics Covered: • What is a Nucleosome? • Histone proteins: H2A, H2B, H3, H4 (core octamer) + H1 (linker) • 146 bp of DNA wrapped around the histone octamer • Linker DNA connecting nucleosomes • "Beads on a string" appearance — 11 nm fibre • Solenoid structure — 30 nm fibre • Euchromatin (loosely packed, active) vs Heterochromatin (tightly packed, inactive) • Levels of DNA compaction in the nucleus • NEET MCQ tips on nucleosome structure ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ Transcript with Timestamp 0:00 DNA packaging: human genome DNA ≈ 2.2 m needs to fit in nucleus 1:33 Woodcock showed repeated thickenings in chromatin fibres = nucleosomes 2:40 Term 'nucleosome' given by Oudet; also called nu bodies 2:50 Nucleosome = histone octamer + DNA wrapped around it 3:26 Histone proteins: rich in lysine & arginine; positively charged; DNA negatively charged 4:06 Histone octamer: H2A, H2B, H3, H4 (2 each = 8 total) 6:09 Core DNA: ~146 bp wrapped around octamer (1.75 turns) 6:45 Linker DNA: ~60 bp between two octamers 7:11 H1 histone: acts as clamp; not part of nucleosome; not inherited ━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━ Amazon Brand Store at https://www.amazon.in/neelabakoretuto.... Complete Study Notes (11th and 12th) are available at: https://amzn.to/3K4Li7k Complete Study Notes for 12th are available at: https://amzn.to/3PRhWjm Complete Study Notes for 11th are available at: https://amzn.to/4uw1hBa The study notes for this unit Genetics & Evolution are available at https://amzn.to/2Sh27jW The study notes for other units: - Diversity in Living World - https://amzn.to/3r8qkyH Structural Organisation in Plants and Animals - https://amzn.to/3r2cxmZ Cell: Structure and Functions - https://amzn.to/2GPagcm Plant Physiology - http://amzn.to/2EZR5HS Human Physiology - http://amzn.to/2DA46ea Reproduction - https://amzn.to/2wu43eS Biotechnology - http://amzn.to/2EZyqf9 Biology in Human Welfare https://amzn.to/4dPRZd7 Ecology https://amzn.to/3RwuOvF ____________________________________________ For business inquiries: abhibakore@gmail.com ___________________________________________ #Nucleosome #HistoneProteins #ChromatinStructure #NEETBiology #MolecularBasisOfInheritance #Class12Biology #neelabakoretutorials